Intelligent Resolution: Integrating Cryo-EM with AI-driven Multi-resolution Simulations to Observe the SARS-CoV-2 Replication-Transcription Machinery in Action

The research using modern Cryo-EM microscopy in combination with artificial intelligence explains the molecular processes of SARS-CoV-2 replication inside the host cell. The obtained results, based on large-scale modelling, can significantly help to find specific drug targets inhibiting SARS-CoV-2 replication and subsequently contribute to the fight against COVID.